2012年12月10日 星期一

【NFkB抗體、NFkB ELISA 套組、NFkB抑制劑】NFkB p65抗體、NFkB p50抗體、NFkB105抗體、p65/RelA

NFkB活化與發炎、癌症生成有密切關係,因此,目前多數研究皆致力於研發NFkB活化之抑制劑,以期具有抗發炎及治療癌症之療效。AbmgoodBIOVISION提供多項研究NFkB之抗體、ELISA KIT、抑制劑。產品種類齊全,是您最佳的選擇


NFkb產品介紹】 NFkB was identified as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is a heterodimer that consists of a 50 kDa DNA binding subunit (p50) and a 65 kDa transactivation subunit (p65/RelA). Both of these subunits exhibit sequence homology to the protooncogene c-Rel. The p50/p65 heterodimer remains in the cytosol in an inactive form as a complex with its inhibitor, IkB. Upon stimulation of cells by a wide variety of stimuli such as lipopolysaccharide (LPS), pro-inflammatory cytokines, and viral infection. IkB is phosphorylated and degraded by proteosome. The active NFkB heterodimer is translocated into the nucleus and induces gene expression.


Product


Size


Concentration


Cat. No.








100ug


1ug/ul


Y011010


$7500




100ug


1ug/ul


Y011011


$7500




100ug


1ug/ul


Y011012


$7500




100ug


1ug/ul


Y011013


$7500




100ug


1ug/ul


Y011014


$7500




100ug


1ug/ul


Y011015


$7500




100ug


1ug/ul


Y011016


$7500




100ug


1ug/ul


Y011017


$7500




100ug


1ug/ul


Y011018


$7500




100ug


1ug/ul


Y011019


$7500




100ug


100ug/100ul


Y011166


$7500




100ug


1ug/ul


Y011217


$7500




100ug


1ug/ul


Y011260


$7500




100ug


100ug/100ul


Y011312


$7500




100ug


1ug/ul


Y021010


$6000




100ug


1ug/ul


Y021011


$6000




100ug


1ug/ul


Y021012


$6000


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